Do your biologic med infusions last between doses? I am on Simponi aria infusions (every 8 weeks) and methotrexate. I am doing very well currently. My Vectra scores are low! (down from high) I am curious to see if others on infusions feel any recurrent symptoms toward the the time their next infusion is due. In other words, does the infusion wear out before you need the next one? I think I do, but they are not like a true flair. Just more tired, achy, etc. I’ve just not seen this in any discussions. Also, how long after your infusion do you feel its effects?